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Anti Plaque Efficacy of Salvadora Persica L. and Green Tea Mouthwash

NCT03790904 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2019-05-14

No results posted yet for this study

Summary

Periodontal diseases and caries are essentially initiated and progressed by accumulation of dental plaque. Thus, daily effective plaque control is valuable as a preventive measure and maintaining oral health. Mechanical plaque control is important but has limitations; therefore, an adjunctive chemical plaque control such as mouthwash is helpful. Various medicinal plant-derived galenicals might be used as safe and stable alternatives to synthetic mouthwashes. For example, a combination of Salvadora persica L. (Sp) root sticks and green tea (Gt) aqueous extract has been found to reduce plaque accumulation over 24 hours. Moreover, these extracts were reported to have anti-microbial activity against many oral bacteria. The objective of this study was to investigate the efficacy of the combination of Gt aqueous extract and Sp aqueous extract in reducing plaque buildup for 4 days duration.

Conditions

  • Periodontal Diseases

Interventions

OTHER

Co.

15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

OTHER

Kin

15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

OTHER

Distilled water

15ml twice a day, rinse for 30sec refrain from eating or drinking for 30min

Sponsors & Collaborators

  • University of Baghdad

    lead OTHER

Principal Investigators

  • Rasha S Abbood · University of Baghdad

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
23 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-10
Primary Completion
2019-03-31
Completion
2019-04-09

Countries

  • Iraq

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03790904 on ClinicalTrials.gov