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The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling

NCT03986307 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2019-06-14

No results posted yet for this study

Summary

Elderly are supplemented with either Omega-3 (3 x 1.1g per day) or placebo (corn oil) during 14 weeks. The last 12 weeks, supplementation is combined with resistance exercise training (3x per week) focusing on upper leg strength. In the present project, the investigators study whether differences in muscle strength and/or muscle mass between conditions can be explained by omega-3-induced effects on systemic or muscle inflammatory signaling, or differences in muscle molecular signaling.

Conditions

  • Aging

Interventions

DIETARY_SUPPLEMENT

Omega-3 polyunsaturated fatty acid supplementation

Daily supplementation with omega-3 capsules (daily for 14 weeks). Each day: 3 capsules of 1.1g

OTHER

Resistance exercise

Resistance exercise training in both supplementation conditions (3 times per week for 12 weeks).

DIETARY_SUPPLEMENT

Placebo - appearance-matched oil supplementation

Daily supplementation with placebo capsules (daily for 14 weeks). Each day: 3 capsules of 1.1g

Sponsors & Collaborators

  • KU Leuven

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-01
Primary Completion
2019-05-25
Completion
2019-05-25

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03986307 on ClinicalTrials.gov