Sleep Disordered Breathing and Alzheimer's Disease Biomarkers in Normal Aging and Mild Cognitive Impairment
NCT03912571 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28
Last updated 2021-09-05
Summary
The purpose of this study is to determine the sleep patterns of subjects with or without sleep disturbances (insomnia, sleep apnea) and compare these findings with their previous FDG/PIB PET, structural MRI and brain blood flow scams performed during their participation in the Following studies 'Alzheimer's Disease Core Center (ADCC) Clinical Evaluation' (IRB: 2942), MRI Progression Markers of Cognitive Decline in the Elderly' (IRB:09-0586), or 'Imaging Neuro inflammation in Alzheimer's Disease with \[11C\] Arachidonic Acid (AA) and PET'(IRB: 10-00442).
Conditions
- Sleep Disorder
Interventions
- DIAGNOSTIC_TEST
-
Structural 3T MRI
measures of global and hippocampal atrophy)
- DIAGNOSTIC_TEST
-
MRI Based Perfusion Imaging
brain blood flow
- DIAGNOSTIC_TEST
-
VR-CO2 MRI Scans
reduced vaso reactivity to carbon dioxide
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Ricardo Osorio, MD · NYU Langone Health
Eligibility
- Min Age
- 55 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-11-13
- Primary Completion
- 2019-09-30
- Completion
- 2019-09-30
Countries
- United States
Study Locations
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