Sleep Disordered Breathing and Alzheimer's Disease Biomarkers in Normal Aging and Mild Cognitive Impairment

NCT03912571 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2021-09-05

No results posted yet for this study

Summary

The purpose of this study is to determine the sleep patterns of subjects with or without sleep disturbances (insomnia, sleep apnea) and compare these findings with their previous FDG/PIB PET, structural MRI and brain blood flow scams performed during their participation in the Following studies 'Alzheimer's Disease Core Center (ADCC) Clinical Evaluation' (IRB: 2942), MRI Progression Markers of Cognitive Decline in the Elderly' (IRB:09-0586), or 'Imaging Neuro inflammation in Alzheimer's Disease with \[11C\] Arachidonic Acid (AA) and PET'(IRB: 10-00442).

Conditions

  • Sleep Disorder

Interventions

DIAGNOSTIC_TEST

Structural 3T MRI

measures of global and hippocampal atrophy)

DIAGNOSTIC_TEST

MRI Based Perfusion Imaging

brain blood flow

DIAGNOSTIC_TEST

VR-CO2 MRI Scans

reduced vaso reactivity to carbon dioxide

Sponsors & Collaborators

Principal Investigators

  • Ricardo Osorio, MD · NYU Langone Health

Eligibility

Min Age
55 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-13
Primary Completion
2019-09-30
Completion
2019-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03912571 on ClinicalTrials.gov