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Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment

NCT06089096 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2025-04-02

No results posted yet for this study

Summary

Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive sequelae. Chronic intermittent hypoxia, sleep fragmentation of OSA, and insufficient sleep have been significantly associated with higher risks of neurocognitive impairment, including mild cognitive impairment (MCI) and Alzheimer's disease. Thus, sleep and circadian function might be modifiable neurocognitive impairment factors.

The significance of the study is to understand the relationships of MCI with sleep apnea and sleep-related symptoms, which helps pave the groundwork for further research.

Conditions

Interventions

DIAGNOSTIC_TEST

Home Sleep Apnea test (HSAT)

Patient will received HSAT at baseline

Sponsors & Collaborators

  • The University of Hong Kong

    lead OTHER

Principal Investigators

  • Sau Man Mary Ip, MD · School of Clinical Medicine, The University of Hong Kong

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-07
Primary Completion
2026-12-31
Completion
2027-03-31

Countries

  • Hong Kong

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06089096 on ClinicalTrials.gov