MedTrace Logo

Effect of Fluid Challenge on Glycocalyx

NCT03891342 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2019-03-27

No results posted yet for this study

Summary

Interventional study comparing effect of two regimes of fluid challenge in patients with sepsis and in patients undergoing elective major surgery on glycocalyx by using perfused Boundary Region in sublingual microcirculation.

Conditions

  • Anesthesia
  • Endothelial Dysfunction
  • Sepsis
  • Septic Shock
  • Surgery

Interventions

DRUG

Fluid bolus administration

Fluid bolus administration either "fast" in 5 minutes or "slow" in 30minutes.

Sponsors & Collaborators

  • University Hospital Pilsen

    collaborator OTHER

  • University Hospital Hradec Kralove

    lead OTHER

Principal Investigators

  • Jan Benes, Assoc.Prof. · Charles University hospital in Plzen, Czech Republic

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-02-29
Primary Completion
2018-07-31
Completion
2018-08-31

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03891342 on ClinicalTrials.gov