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Bioavailability of Carotenoids Present in Mamey Sapote (Pouteria Sapota (Jacq.) H. E. Moore & Stearn) Fruit

NCT03873909 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2019-03-14

No results posted yet for this study

Summary

The goal of the study is to determine if mamey sapote fruit, rich in rare potentially provitamin A keto-carotenoids, is a good source of vitamin A in humans. Furthermore, it will help to compare the absorption of carotenoids between the fruit versus a "matrix-free" formulation.

The objective will be accomplished by quantitation of the immediate post-prandial plasma concentrations of parent carotenoids and vitamin A metabolites from participants consuming a meal consisting of a mamey sapote fruit smoothie or a shake containing mamey sapote encapsulated carotenoids.

Conditions

  • Biological Availability

Interventions

OTHER

Fruit Smoothie

Fruit Smoothie with 150-200 g mamey sapote fruit

OTHER

Matrix-Free Shake

Shake containing mamey sapote extracted carotenoids (2 g, 845 µg sapotexanthin and 1.21-1.51 mg cryptocapsin

Sponsors & Collaborators

  • Universidad de Costa Rica

    collaborator OTHER

  • University of Hohenheim

    lead OTHER

Principal Investigators

  • Patricia Esquivel, Ph.D · Universidad de Costa Rica

  • Silvia Quesada · Universidad de Costa Rica

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-10-01
Primary Completion
2017-11-13
Completion
2018-03-13

Countries

  • Costa Rica
  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03873909 on ClinicalTrials.gov