MedTrace Logo

Fluid Responsiveness in HFNC Patients

NCT03817996 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2019-08-13

No results posted yet for this study

Summary

The plethysmographic variation index (PVi) is a measure of the respiratory-induced variations in the plethysmographic waveform. Interestingly, in mechanically ventilated patients and under certain conditions, PVi may reflect fluid responsiveness (FR).

Patients treated with high flow nasal cannula (HFNC), which has been described as a useful supportive therapy in spontaneously breathing patients with respiratory failure, may present the same hemodynamic changes, measured by transthoracic echocardiography, as those patients who are mechanically ventilated (MV). The hypothesis of the present study is that the PVi may predict FR in HFNC patients and, therefore, the objective is to investigate whether the PVi can predict FR in patients treated with HFNC.

Conditions

  • Respiratory Insufficiency
  • Shock, Septic
  • Sepsis

Interventions

OTHER

Fluid challenge

250ml of saline in Responders (those who increased \>10% their cardiac output after a passive leg raising maneuver).

Sponsors & Collaborators

  • Hospital Universitari Vall d'Hebron Research Institute

    lead OTHER

Principal Investigators

  • Oriol Roca, MD PhD · Hospital Vall d'Hebron

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2019-03-30
Completion
2019-04-30

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03817996 on ClinicalTrials.gov