MedTrace Logo

Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia

NCT04971148 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2023-08-14

No results posted yet for this study

Summary

In this study, patients who are ready for extubation and indicated for high-flow nasal cannula therapy after extubation will be enrolled, the investigators would measure the patient peak tidal inspiratory flow (PTIF) pre and post extubation to explore the correlation between the two PTIFs. Moreover, different HFNC flows would be applied, to explore the patient response in terms of oxygenation and lung aeration to different flow ratios that matched and are above post-extubation PTIF.

Conditions

  • Hypoxemic Respiratory Failure

Interventions

OTHER

HFNC flow set at patient peak tidal inspiratory flow

HFNC flow will be set at the level equal to patient peak tidal inspiratory flow

OTHER

HFNC flow set at 1.33 times of patient peak tidal inspiratory flow

HFNC flow will be set at 1.33 times of patient peak tidal inspiratory flow

OTHER

HFNC flow set at 1.67 times of patient peak tidal inspiratory flow

HFNC flow will be set at 1.67 times of patient peak tidal inspiratory flow

OTHER

HFNC flow set at 2 times of patient peak tidal inspiratory flow

HFNC flow will be set 2 times of patient peak tidal inspiratory flow

Sponsors & Collaborators

  • Hospital Vall d'Hebron

    collaborator OTHER

  • Rush University Medical Center

    lead OTHER

Principal Investigators

  • Jie Li, PhD · Rush University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-07
Primary Completion
2023-08-08
Completion
2023-08-08

Countries

  • United States
  • Spain

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04971148 on ClinicalTrials.gov