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Effect of Aging on Cortical Excitability and Motor Learning

NCT03750903 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-04-03

Study results available
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Summary

The objective of the current proposal is to identify 1) how aging-related changes in GABAergic cortical inhibition affect motor performance, and 2) how aerobic exercise may improve inhibitory function and facilitate motor learning.

Conditions

  • Aging

Interventions

BEHAVIORAL

Aerobic Exercise

Participants will engage in an aerobic exercise program meeting thrice weekly for a period of 12 weeks.

BEHAVIORAL

Stretching and Balance Training

Participants will engage in a balance and stretching comparator condition meeting thrice weekly for 12 weeks.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Joe R. Nocera, PhD · Atlanta VA Medical and Rehab Center, Decatur, GA

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-04
Primary Completion
2023-09-30
Completion
2024-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03750903 on ClinicalTrials.gov