MedTrace Logo

Cause-effect Relationships Between Brain Networks and Bimanual Coordination in Older Adults

NCT04349137 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2021-08-30

No results posted yet for this study

Summary

In this study, high-definition dual-site transcranial alternating current stimulation (i.e., non-invasive brain stimulation) will be applied to boost the fronto-parietal network during a bimanual coordination task in healthy young and older adults. Previous studies indicated that this network is important in initial motor learning, possibly through its role in spatial working memory. Therefore, stimulation will be applied during both a pure spatial working memory test, and during a bimanual coordination task.

It is also shown that healthy older adults do not engage spatial working memory brain regions during motor learning, which is related to worse motor learning. Therefore, the investigators will investigate whether this type of stimulation can improve bimanual motor learning in healthy older adults.

Conditions

  • Healthy Aging
  • Healthy

Interventions

DEVICE

HD-tACS

non-invasive high-definition dual-site transcranial alternating current stimulation (HD-tACS) low intensive electrical alternating currents (2 mA peak-to-peak) are externally applied to the skull at a frequency of 6Hz to entrain endogenous neural oscillatory activity.

DEVICE

sham HD-tACS

sham non-invasive high-definition dual-site transcranial alternating current stimulation (HD-tACS)

Sponsors & Collaborators

  • Hasselt University

    lead OTHER

Principal Investigators

  • Bart Van Wijmeersch, prof. dr. · Hasselt University

  • Raf Meesen, prof. dr. · Hasselt University

  • Stefanie Verstraelen, drs. · Hasselt University

  • Kim van Dun, dr. · Hasselt University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
65 Years
Max Age
77 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2021-09-30
Completion
2021-09-30

Countries

  • Belgium

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04349137 on ClinicalTrials.gov