Trophic Nutrition in Patients Submitted to High Flow Oxygen Therapy and / or Non Invasive Mechanical Ventilation

Summary

The decision about the initiation of enteral nutrition therapy in critically ill patients with oxygen therapy needs with HFC and / or NIMV is a matter of debate at present. Despite the benefits associated with this practice in critically ill patients, the scarcity of clinical studies in patients with sufficient methodological quality, as well as the absence of specific recommendations on enteral nutrition therapy in this type of patient, generates controversy in the professionals involved in critical patient care.

Conditions

• Noninvasive Ventilation
• Trophic Nutrition

Interventions

PROCEDURE

Trophic Nutrition

According to previously published studies of Trophic Nutritions in critically ill patients, an energy goal of 20-30% estimated caloric needs of 20-30 kcal / kg and a protein intake of 1.2 to 2.0 g / kg / day of proteins will be established. at most 72 hours after the start of nutritional therapy. The rhythm of initiation and increase of enteral contributions will be at the discretion of each participating ICU. Prokinetic or parenteral nutrition (PN) complementary will not be used routinely, leaving its indication at the discretion of the responsible physician. A hyperproteic nutritional formula (10 g / 100 ml) will be used, with a caloric intake of 1.2 kcal / ml and a non-protein kcal / nitrogen ratio of 52: 1. TN will be administered over 23 hours each day by continuous infusion pump. The head of the patient's bed will rise above 30° as much as possible to reduce the risk of aspiration. The Gastric Residue Volume (GRV) will be measured every 24 hours.

Sponsors & Collaborators

• Hospital Universitario de Gran Canaria Doctor Negrín

  collaborator UNKNOWN

• Hospital Universitario Fundación Jiménez Díaz

  collaborator OTHER

• Hospital Barbastro

  collaborator UNKNOWN

• Hospital del Rio Hortega

  collaborator OTHER

• Hospital Universitario Infanta Cristina

  collaborator OTHER

• Hospital Universitario Ramon y Cajal

  collaborator OTHER

• University Hospital of Girona Dr. Josep Trueta

  collaborator NETWORK

• Hospital Universitario Infanta Leonor

  collaborator OTHER

• Hospital Regional Universitario Carlos Haya

  collaborator OTHER

• Hospital de Cruces

  collaborator OTHER

• Hospital Universitario 12 de Octubre

  collaborator OTHER

• Hospital Universitario Virgen de la Arrixaca

  collaborator OTHER

• Hospital Virgen de la Concha

  collaborator UNKNOWN

• Hospital Universitario de Torrevieja

  collaborator UNKNOWN

• Complejo Hospitalario Universitario de Santiago

  collaborator OTHER

• Hospital Universitario Puerto Real

  collaborator OTHER

• Hospital Miguel Servet

  collaborator OTHER

• Hospital Universitario Severo Ochoa

  collaborator UNKNOWN

• Hospital Universitario La Fe

  collaborator OTHER

• Hospital San Carlos, Madrid

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-01-01

Primary Completion

2023-08-01

Completion

2024-02-01

Countries

• Spain

Study Locations