Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
NCT03719495 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 68
Last updated 2024-05-16
Summary
The purpose of this research study is to learn about the effects that standard of care endocrine therapies have on the immune system's response to cancer by looking at the number and types of immune cells present and how they function in women with early stage estrogen receptor positive (ER+) breast cancer.
Conditions
- Breast Cancer
- Estrogen Receptor-positive Breast Cancer
- Healthy
Sponsors & Collaborators
-
United States Department of Defense
collaborator FED - lead OTHER
Principal Investigators
-
Susan Dent, MD · Duke University
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-06-19
- Primary Completion
- 2023-07-31
- Completion
- 2023-07-31
Countries
- United States
Study Locations
More Related Trials
-
Single Dose Partial Breast Radiotherapy
NCT00944528 ·Status: COMPLETED ·Phase: PHASE1
-
FES BPET-DBT in Newly Diagnosed Breast Cancer
NCT05659797 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery
NCT06127979 ·Status: RECRUITING ·Phase: NA
-
Imaging Biomarker for Early Detection of Treatment Efficacy During Breast Cancer Neoadjuvant Chemotherapy
NCT02679586 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab
NCT05877859 ·Status: RECRUITING
-
Immunomonitoring of Breast Cancer Patients During Systemic Treatment
NCT04925856 ·Status: RECRUITING ·Phase: NA
-
The Immune System's Response to Young Women's Breast Cancer
NCT01503190 ·Status: RECRUITING
-
MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ
NCT02352883 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Assessment of the Decision-making Impact of the Breast Cancer Index in Recommending Extended Adjuvant Endocrine Therapy for Patients With Early Stage ER-positive Breast Cancer
NCT02057029 ·Status: COMPLETED ·Phase: NA
-
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
NCT01766297 ·Status: RECRUITING ·Phase: PHASE2
-
The Impact of the Oncotype DX® Breast Cancer Assay on Treatment Decisions in a Canadian Population
NCT02347449 ·Status: COMPLETED ·Phase: NA
-
The Effects of HER2 Receptor Signaling on Human Brown Fat Activity
NCT06222957 ·Status: RECRUITING
-
Establishment of Normal Breast Epithelial Cell Lines From Patients at High Risk for Breast Cancer
NCT00001496 ·Status: COMPLETED
-
Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
NCT05717998 ·Status: ACTIVE_NOT_RECRUITING
-
Studying Tissue Samples From Women With Breast Cancer Who Were Treated on Clinical Trial NCCTG-N9831
NCT00898898 ·Status: COMPLETED
-
Diffusion Weighted MR Imaging of the Breasts in Women at High Risk of Breast Cancer: A Pilot Study
NCT01938157 ·Status: COMPLETED ·Phase: NA
-
Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery
NCT00033397 ·Status: COMPLETED
-
Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer
NCT01407770 ·Status: COMPLETED
-
Pre-Operative, Single-Dose Ipilimumab and/or Cryoablation in Early Stage/Resectable Breast Cancer
NCT01502592 ·Status: COMPLETED ·Phase: PHASE1
-
Hybrid Molecular Imaging of ER in Breast Cancer Patients With DCIS
NCT03703492 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography
NCT02455453 ·Status: COMPLETED ·Phase: PHASE2
-
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
NCT04517838 ·Status: RECRUITING
-
Long Term Follow-Up in Patients With Stage 0-IIIC Breast Cancer
NCT04661982 ·Status: ACTIVE_NOT_RECRUITING
-
S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer
NCT03723928 ·Status: RECRUITING ·Phase: NA
-
Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment
NCT05926024 ·Status: ACTIVE_NOT_RECRUITING