Role of the Immune Environment in Response to Therapy in Breast Cancer
NCT05396612 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-07-08
Summary
This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.
Conditions
- Breast Cancer
- ER Positive Breast Cancer
- HER2-negative Breast Cancer
- TNBC - Triple-Negative Breast Cancer
Interventions
- OTHER
-
Collection of personal health information from women treated at the University of Pennsylvania under an approved HIPAA waiver.
Collection of personal health information from women treated at the University of Pennsylvania under an approved HIPAA waiver.
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Jennifer Zhang, MD · Abramson Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-10-03
- Primary Completion
- 2032-12-31
- Completion
- 2032-12-31
Countries
- United States
Study Locations
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