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Assessment of Immediate Implant Stability When Adding Mixture of Hyaluronic Acid and Melatonin

NCT03692026 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2018-10-03

No results posted yet for this study

Summary

Placing implants immediately after tooth extraction offers several advantages such as preventing bone resorption, maintaining alveolar crest width and height, reducing surgical procedures and treatment time, in addition to good esthetic results. Immediate implant placement after tooth extraction is often associated with a residual gap between the implant surface and the residual bone walls. Osseointegration between the implant surface and the surrounding osseous walls of the extraction socket should increase using materials that promote new bone formation. Since both melatonin and hyaluronic acid are thought to have a positive effect on increasing osseointegration and decreasing inflammation of the tissues; the investigators want to test if adding a mix of hyaluronic acid and melatonin to immediately implant, will give a better implant stability, decreased peri-implant bone loss and decreased post-operative pain versus immediate implant placement without adding any material.

Conditions

  • Immediate Dental Implant

Interventions

PROCEDURE

Immediate implant placement

implants will be placed in freshly extraction sockets with or without application of Hyaluronic acid and Melatonin mixture.

DRUG

Hyaluronic acid and Melatonin Mixture

a mixture of hyaluronic acid and melatonin will be prepared and added topically to the implant surface, extraction socket and peri-implant area for the study group

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Mona Darhous, PhD · Professor of Periodontology. Faculty of Oral and Dental Medicine. Cairo University

  • Mona Shoeib, PhD · Professor of Periodontology. Faculty of Oral and Dental Medicine. Cairo University

  • Ahmed El Barbary, PhD · Ass. Professor of Periodontology. Faculty of Oral and Dental Medicine. Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-10-31
Primary Completion
2020-02-29
Completion
2020-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03692026 on ClinicalTrials.gov