The Cardiovascular Effects of Electronic Hookah Vaping
NCT03690427 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2023-08-16
Summary
Hookah (water-pipe) tobacco smoking has quickly grown to become a major global tobacco epidemic among youth; with electronic (e-) hookahs more recently increasing in popularity especially among young female adults, who endorse marketing claims that these products are a safer alternative to traditional hookah, but scientific evidence is lacking. The study aims to elucidate the comparative effects of traditional hookah smoking vs. e-hookah vaping on human vascular and endothelial function; and examine the role of inflammation and oxidative stress, as likely mechanisms in hookah-related cardiovascular disease pathogenesis.
Conditions
- Endothelial Dysfunction
- Inflammation
- Oxidative Stress
Interventions
- OTHER
-
Traditional hookah smoking
Charcoal-heated hookah smoking
- OTHER
-
Electronic hookah vaping
Electronic hookah bowl inhalation
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of California, Los Angeles
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 21 Years
- Max Age
- 39 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-12-11
- Primary Completion
- 2021-08-31
- Completion
- 2021-09-27
Countries
- United States
Study Locations
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