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Vascular EffectS of regUlar Cigarettes Versus electronIc Cigarette USe

NCT02878421 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 145

Last updated 2019-02-06

No results posted yet for this study

Summary

The purpose of this study is to assess the effects of electronic cigarettes-nicotine and electronic cigarette-nicotine free on endothelial function as compared to traditional cigarettes. Due to ethical reasons, we cannot fully randomise all particpants to the three arms.

Participants who wish to quit smoking will be randomized to

1. Switch to electronic cigarettes containing nicotine plus flavor
2. Switch to electronic cigarettes containing flavor alone Those who do not wish to quit smoking will continue on the Tobacco Cigarette arm Treatment period will be 28 days

Conditions

  • Vascular Diseases

Interventions

DEVICE

electronic cigarette + 16mg nicotine & flavor

comparison of different strengths of nicotine

OTHER

electronic cigarette + 0mg nicotine & flavor

comparison of different strengths of nicotine

OTHER

Tobacco cigarette

Participant to remain on traditional cigarettes for 28 days

Sponsors & Collaborators

  • NHS Tayside

    collaborator OTHER_GOV

  • British Heart Foundation

    collaborator OTHER

  • University of Dundee

    lead OTHER

Principal Investigators

  • Jacob George · University of Dundee

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-08-18
Primary Completion
2018-07-31
Completion
2018-07-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02878421 on ClinicalTrials.gov