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Clinical Pharmacology of Electronic Cigarettes

NCT02470754 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 38

Last updated 2023-06-22

Study results available
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Summary

The purpose of this study is to learn more about nicotine exposure and the safety of electronic cigarettes (EC). It will focus on the areas that are thought to most closely relate to the addictive potential of EC, namely: (1) EC as nicotine delivery devices, covering issues of nicotine intake and pharmacokinetics, temporal patterns of use and titration of nicotine; and (2) subjective effects of EC use, including relationship of use to reward, withdrawal and craving.

Conditions

  • Nicotine Dependence

Interventions

DEVICE

Tobacco Cigarette

Usual brand tobacco cigarette smoked by study participant.

DEVICE

Electronic Cigarette

Usual brand electronic cigarettes smoked by study participant.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Roswell Park Cancer Institute

    collaborator OTHER

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • University of California, San Francisco

    lead OTHER

Principal Investigators

  • Neal L Benowitz, MD · University of California, San Francisco

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-07-23
Primary Completion
2018-02-02
Completion
2018-02-02

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02470754 on ClinicalTrials.gov