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Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

NCT04053868 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2025-10-16

Study results available
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Summary

This is an observational, crossover design that will examine the pharmacokinetics and pharmacodynamics of impact of smoking tobacco cigarettes or vaping the JUUL electronic cigarette.

Conditions

  • Nicotine Administration & Dosage
  • E-cigarettes
  • Vaping
  • E-Liquid
  • Tobacco Smoking

Interventions

OTHER

JUUL

Electronic Cigarette

OTHER

Tobacco

Tobacco Cigarette

Sponsors & Collaborators

Principal Investigators

  • Neal L Benowitz, MD · University of California, San Francisco

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-12-09
Primary Completion
2022-03-31
Completion
2022-03-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04053868 on ClinicalTrials.gov