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Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

NCT02179034 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 59

Last updated 2020-05-04

No results posted yet for this study

Summary

This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers. The hypothesis is that the combination of nicotine and menthol, when compared with menthol or nicotine alone, will result in greater increase in liking of an e-cigarette and greater reduction in nicotine withdrawal.

Conditions

  • Nicotine Dependence, Other Tobacco Product

Interventions

DRUG

Nicotine

Participants will receive no nicotine, low dose nicotine (6 mg/ml) or high dose nicotine (12 mg/ml)

OTHER

Low Dose Menthol

A low dose of menthol will be added to the tobacco flavor.

OTHER

High Dose Menthol

A high dose of menthol will be added to the tobacco flavor.

Sponsors & Collaborators

  • Yale University

    lead OTHER

Principal Investigators

  • Dana Cavallo, PhD · Yale University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-23
Primary Completion
2016-07-18
Completion
2017-06-12

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02179034 on ClinicalTrials.gov