North American Prodromal Synucleinopathy Consortium

Summary

This study will enroll participants with idiopathic rapid eye movement (REM) sleep behavior disorder (RBD), for the purpose of preparing for a clinical trial of neuroprotective treatments against synucleinopathies.

Conditions

• REM Sleep Behavior Disorder
• Parkinson Disease
• Lewy Body Disease
• Dementia With Lewy Bodies
• Multiple System Atrophy
• REM Sleep Parasomnias

Sponsors & Collaborators

• Mayo Clinic

  collaborator OTHER

• University of Minnesota

  collaborator OTHER

• University of California, Los Angeles

  collaborator OTHER

• McGill University

  collaborator OTHER

• Emory University

  collaborator OTHER

• Massachusetts General Hospital

  collaborator OTHER

• National Institute on Aging (NIA)

  collaborator NIH

• Stanford University

  collaborator OTHER

• Portland VA Medical Center

  collaborator FED

• Banner Health

  collaborator OTHER

• Washington University School of Medicine

  lead OTHER

Principal Investigators

• Yo-El Ju, MD · Washington University School of Medicine

• Bradley Boeve, MD · Mayo Clinic

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-08-29

Primary Completion

2026-07-31

Completion

2026-07-31

Countries

• United States
• Canada

Study Locations