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Neuroimaging Studies of Reward Processing in Depression

NCT03026036 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 123

Last updated 2023-02-03

No results posted yet for this study

Summary

This study investigates stress-related signaling of glutamate and dopamine within the reward-processing circuit in Major Depressive Disorder (MDD), and whether they can be used to predict depressive symptoms in the future. This will be achieved through various neuroimaging tools (MRS, fMRI, PET), behavioral tasks, and a naturalistic follow-up design.

Conditions

Interventions

RADIATION

PET Scan with Raclopride

A subsample (21 per group) will complete the PET imaging.

Sponsors & Collaborators

  • Mclean Hospital

    lead OTHER

Principal Investigators

  • Diego A Pizzagalli, Ph.D. · Mclean Hospital

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2021-03-31
Completion
2021-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03026036 on ClinicalTrials.gov