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Oral Amantadine, IV Amantadine and Hemodynamic Response to Laryngoscopy

NCT03612921 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2021-11-16

No results posted yet for this study

Summary

this study will be undertaken-to evaluate the effect of oral amantadine versus IV amantadine premedication on the hemodynamic response to laryngoscopy ,tracheal intubation and surgical incision and their effect on β-endorphins.

Conditions

  • Intubation, Intratracheal

Interventions

DRUG

oral Amantadine sulfate

oral amantadine

DRUG

i.v Amantadine Sulfate

intra venous amantadine

DRUG

placebo tablet

placebo tablet

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Ghada Abu El Fadl, MD · Assiut, Assiut governorate, Egypt, 715715

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-15
Primary Completion
2022-03-01
Completion
2022-04-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03612921 on ClinicalTrials.gov