Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response
NCT06374017 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120
Last updated 2025-04-02
Summary
Many studies discussed attenuating stress response by various measures but to the interest of our study , No one compared topical spray of both lidocaine and dexmedetomidine in attenuating the haemodynamic stress responses of laryngoscopy and endotracheal intubation, avoiding undesired systemic effects of drugs ,
Conditions
- To Measure Systolic Blood Pressure Postintubation
Interventions
- DRUG
-
Normal saline, Lidocaine, dexmetomidine
The study drug of each group will be sprayed into oropharynx, the vocal cords and tracheal tree 3 minutes after induction of anesthesia and 5 minutes before intubation.
Sponsors & Collaborators
-
Kasr El Aini Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-04-20
- Primary Completion
- 2024-12-30
- Completion
- 2025-01-10
Countries
- Egypt
Study Locations
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