The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation
NCT01289769 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2011-12-15
Summary
The purpose of this study is to evaluate the effect of dexmedetomidine on hemodynamic responses during laryngoscopy and double lumen endotracheal intubation and assess the adverse effect related to complications of dexmedetomidine.
Conditions
- Intubation Complication
- Tracheal Intubation Morbidity
- Anesthesia Intubation Complication
- Hypertension
- High Blood Pressure
- Tachycardia
Interventions
- DRUG
-
Dexmedetomidine
dexmedetomidine 0.7 microgram per kilogram in saline 20 ml given within 10 minutes before intubation
- DRUG
-
normal saline 20 ml( the same volume as dexmedetomidine) giving within 10 minutes.
Sponsors & Collaborators
-
Chiang Mai University
lead OTHER
Principal Investigators
-
Tanyong Pipanmekaporn, MD · Department of Anesthesiology, Faculty of Medicine, Chiang Mai University , Chiang Mai, Thailand,50200
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-03-31
- Primary Completion
- 2011-12-31
- Completion
- 2011-12-31
Countries
- Thailand
More Related Trials
-
Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
NCT04659057 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
NCT02162433 ·Status: TERMINATED ·Phase: PHASE4
-
Antitussive Effect of Single-dose Dexmedetomidine With Low-dose Remifentanil Infusion
NCT02208505 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Dexmedetomidine for Cough Suppression in Patients Undergoing Thyroid Surgery
NCT03312413 ·Status: UNKNOWN ·Phase: PHASE4
-
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
NCT05657028 ·Status: UNKNOWN ·Phase: NA
-
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
NCT06712186 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Attenuation Of Hemodynamic Response To Laryngoscopy. Role Of Dexmedetomidine. A Dose Finding Study
NCT05909215 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine or Lidocaine for Lessening the Hemodynamic Responses to Laryngoscopy and Intubation
NCT05941767 ·Status: COMPLETED ·Phase: NA
-
Effect of Dexmedetomidine After Thyroidectomy
NCT02412150 ·Status: COMPLETED ·Phase: NA
-
Application of Dexmedetomidine Hydrochloride Injection in Anesthesia for Patients Without Tracheal Intubation
NCT04652427 ·Status: UNKNOWN ·Phase: NA
-
The Effect of Dexmedetomidine for Emergence Cough
NCT03622502 ·Status: COMPLETED ·Phase: NA
-
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
NCT06573957 ·Status: COMPLETED ·Phase: NA
-
Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.
NCT03204006 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine for Laryngeal Mask Airway Insertion
NCT01852539 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Single-dose Dexmedetomidine on Emergence Excitement in Adults With Nasotracheal Intubation After Orthognathic Surgery
NCT01524367 ·Status: COMPLETED ·Phase: PHASE4
-
Intramuscular Dexmedetomidine as Premedication
NCT01937611 ·Status: UNKNOWN ·Phase: PHASE4
-
Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
NCT00345384 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation?
NCT07165483 ·Status: RECRUITING ·Phase: NA
-
Dexmedetomidine for Attenuation of Pressor Response
NCT06592027 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Dexmedetomidine to Postoperative Awakening and Extubation-related Changes in Blood Pressure
NCT01871129 ·Status: COMPLETED ·Phase: PHASE4
-
Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia
NCT02007798 ·Status: UNKNOWN ·Phase: NA
-
Hemodynamic Response to Intubation
NCT02844894 ·Status: UNKNOWN ·Phase: PHASE4
-
Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings
NCT07298525 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Comparison of Dexmedetomidin and Remifentanil for the Effect on Airway Reflex and Hemodynamic Response During Emergence in Patients Undergoing Craniotomy
NCT01365923 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine vs Control on Attenuation Hemodynamic Response to Noxious Stimuli in CABG Surgical Patients
NCT06238011 ·Status: NOT_YET_RECRUITING ·Phase: NA