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Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers

NCT04659642 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2021-03-10

No results posted yet for this study

Summary

The aim of this blind comparative study was to compare the effects of dexmedetomidine, fentanyl and their combination on airway reflexes and hemodynamic responses to tracheal extubation in Adult chronic male smoking patients scheduled for abdominal surgeries (of average 2-3 hours duration).

Conditions

  • Airway Responses
  • Hemodynamic

Interventions

DRUG

Dexmedetomidine Injection [Precedex]

the drug is given 15 minutes before the estimated end of surgery

DRUG

Fentanyl Citrate Injection

the drug is given 15 minutes before the estimated end of surgery

COMBINATION_PRODUCT

dexmedetomidine and fentanyl

the combination of the two drugs with the same used doses is given 15 minutes before the estimated end of surgery

Sponsors & Collaborators

  • National Cancer Institute, Egypt

    lead OTHER

Principal Investigators

  • naglaa abdullah, prof · NCI, Cairo university

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-11-30
Primary Completion
2021-03-06
Completion
2021-03-20
FDA Drug
Yes

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04659642 on ClinicalTrials.gov