Tranexamic Acid in Major Orthopedic Surgery: Comparison of 3 Dosage Regimen
NCT03573245 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 210
Last updated 2018-06-29
Summary
Tranexamic acid has been shown to be effective in reducing blood loss and transfusion in orthopedic surgery. It remains unknown the ideal therapeutic regimen. The goal of this study is to compare 3 dosage regimen of tranexamic acid in patients submitted to major orthopedic surgery.
Conditions
- Tranexamic Acid
- Knee Osteoarthritis
- Ankle Osteoarthritis
- Bleeding
Interventions
- DRUG
-
Tranexamic Acid
Tranexamic acid effect on perioperative bleeding in orthopedic surgery
Sponsors & Collaborators
-
CUF Santarém Hospital
lead OTHER
Principal Investigators
-
Angela Sa, MD · CUF Santarem Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-07-01
- Primary Completion
- 2019-04-01
- Completion
- 2019-04-01
More Related Trials
-
Tranexamic Acid in Orthopaedic Trauma Surgery
NCT02080494 ·Status: UNKNOWN ·Phase: NA
-
Two Different Administration Methods of Tranexamic Acid on Perioperative Blood Loss During Total Hip Arthroplasty
NCT03157401 ·Status: COMPLETED
-
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
NCT03074994 ·Status: UNKNOWN ·Phase: PHASE2
-
The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis
NCT02458729 ·Status: COMPLETED ·Phase: PHASE4
-
Serial Use of Intravenous and Oral Tranexamic Acid in Primary Total Knee Arthroplasty Patients
NCT03109652 ·Status: UNKNOWN ·Phase: PHASE4
-
Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid
NCT03915756 ·Status: UNKNOWN ·Phase: NA
-
Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty
NCT01370460 ·Status: COMPLETED ·Phase: PHASE2
-
Tranexamic Acid for Total Knee Arthroscopy
NCT04443920 ·Status: COMPLETED ·Phase: PHASE4
-
Tranexamic Acid in Total Hip Arthroplasty.
NCT02252497 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty
NCT06638749 ·Status: WITHDRAWN ·Phase: PHASE3
-
Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty
NCT01651806 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty
NCT02323373 ·Status: COMPLETED ·Phase: PHASE2
-
Visual Field Infiltration of Tranexamic Acid Reduced the Blood Loss in Total Knee Arthroplasty
NCT03934047 ·Status: UNKNOWN ·Phase: NA
-
Use of Tranexamic Acid in the Total Knee Arthroplasty.
NCT05919615 ·Status: COMPLETED ·Phase: NA
-
Tranexamic Acid in Revision Total Joint Arthroplasty
NCT02877381 ·Status: COMPLETED ·Phase: PHASE4
-
Intra-articular Tranexamic Acid in the Reduction of Blood Transfusions in Primary Total Hip and Total Knee Arthroplasty
NCT02393963 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison Between Low Dose and High Dose Intra-articular Tranexamic Acid in Total Knee Arthroplasty
NCT03044041 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement
NCT01850394 ·Status: COMPLETED ·Phase: NA
-
Alteration of Thrombelastography and Coagulation Function in Patients Undergoing Total Knee Arthroplasty With Intra-articular Tranexamic Acid Administration
NCT05490160 ·Status: UNKNOWN
-
Evaluation of Intraarticular Tranexamic Acid to Reduction of Total Blood Loss Following Knee-Arthroplasty
NCT02427412 ·Status: COMPLETED ·Phase: PHASE4
-
Thromboelastogram During Total Knee Replacement
NCT02373969 ·Status: COMPLETED
-
Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty
NCT03690037 ·Status: COMPLETED ·Phase: PHASE4
-
Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement.
NCT03365999 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
NCT04085575 ·Status: COMPLETED ·Phase: PHASE4
-
Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty
NCT06832878 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4