The European Commission expanded Hympavzi approval to patients 12 and older with hemophilia A or B with inhibitors. Phase 3 data showed a 93% reduction in mean treated annualized bleeding rate versus on-demand therapy.
AstraZeneca's CALQUENCE received FDA approval as the first all-oral, fixed-duration regimen for chronic lymphocytic leukemia, while the EMA validated the marketing authorization application for ENHERTU in HER2-positive breast cancer treatment.
International researchers have identified a specific antibody mutation that causes rare but serious blood clots after adenovirus-based COVID-19 vaccines or natural adenovirus infection, providing a roadmap for safer vaccine design.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07523880 |
Multi-Omics-Based Novel Thrombosis and Bleeding Markers and Risk Model for CHD |
RECRUITING | |
| NCT07471139 |
SWITCH: Apixaban vs Vitamin K in HM3 |
NOT_YET_RECRUITING | PHASE3 |
| NCT07450755 |
Concomitant PFA Bsaed PVI Plus LAAC |
NOT_YET_RECRUITING | NA |
| NCT07401394 |
BAR-TAX - Tranexamic Acid in Bariatric Surgery. |
ACTIVE_NOT_RECRUITING | NA |
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Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study) |
NOT_YET_RECRUITING | NA |
| NCT07366606 |
Bleeding Management İn Open Heart Surgery |
NOT_YET_RECRUITING | NA |
| NCT07358416 |
Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery. |
ACTIVE_NOT_RECRUITING | |
| NCT07354789 |
The Feasibility, Safety, and Efficacy of EUS-Guided PSE: A Cohort Study |
NOT_YET_RECRUITING | NA |
| NCT07352072 |
Incidence of Bleeding, Thrombosis and Transfusion Requirements in ICU Patients With COVID-19 Supported With Veno-venous Extracorporeal Membrane Oxygenation |
NOT_YET_RECRUITING | |
| NCT07309848 |
Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs |
RECRUITING |
