Grifols has launched FESILTY (fibrinogen, human-chmt) in the U.S., a fibrinogen concentrate FDA-approved in December 2025 for acute bleeding episodes in patients with congenital fibrinogen deficiency. The highly purified product, developed by Biotest, enables rapid fibrinogen restoration and can be reconstituted in approximately three minutes.
The European Commission expanded Hympavzi approval to patients 12 and older with hemophilia A or B with inhibitors. Phase 3 data showed a 93% reduction in mean treated annualized bleeding rate versus on-demand therapy.
Alzheimer's blood tests are gaining FDA clearances and strong patient interest, yet surveys show clinicians remain skeptical about their reliability and clinical benefit. A UK survey found fewer than one-third of psychiatrists have used biomarkers, while only 6% of memory services meet access guidelines. An ethical framework urges careful implementation, especially in primary care.
AstraZeneca's CALQUENCE received FDA approval as the first all-oral, fixed-duration regimen for chronic lymphocytic leukemia, while the EMA validated the marketing authorization application for ENHERTU in HER2-positive breast cancer treatment.
International researchers have identified a specific antibody mutation that causes rare but serious blood clots after adenovirus-based COVID-19 vaccines or natural adenovirus infection, providing a roadmap for safer vaccine design.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07772700 |
Potassium-competitive Acid Blocker Versus Double Dose Proton Pump Inhibitors in High High-risk Peptic Ulcer Bleeding |
NOT_YET_RECRUITING | NA |
| NCT07737366 |
The Efficacy of Lavender Herbal Tea in Premenstrual Syndrome |
COMPLETED | NA |
| NCT07644247 |
STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump |
NOT_YET_RECRUITING | PHASE4 |
| NCT07640399 |
Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis |
COMPLETED | NA |
| NCT07638930 |
Colibricare Efficacy on Oral Surgical Procedures/Extraction Wound and Gingiva Retraction |
COMPLETED | NA |
| NCT07627789 |
This Study Aims to Assess the Impact of 50°C Saline Irrigation on the Overall Intraoperative Blood Loss and Surgical Visualization During Endoscopic Sinus Surgery for Rhinosinusitis. |
COMPLETED | NA |
| NCT07523880 |
Multi-Omics-Based Novel Thrombosis and Bleeding Markers and Risk Model for CHD |
RECRUITING | |
| NCT07471139 |
SWITCH: Apixaban vs Vitamin K in HM3 |
NOT_YET_RECRUITING | PHASE3 |
| NCT07450755 |
Concomitant PFA Bsaed PVI Plus LAAC |
NOT_YET_RECRUITING | NA |
| NCT07401394 |
BAR-TAX - Tranexamic Acid in Bariatric Surgery. |
ACTIVE_NOT_RECRUITING | NA |
