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Reduction Bleeding in Laminectomy With Double Doses of Tranexamic Acid

NCT01643135 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2013-12-18

No results posted yet for this study

Summary

Tranexamic acid has benn widely used to reduce perioperative bleeding in several operations such as cardiac surgery, liver transplant and joint arthroplasty with good results. Few studies in laminectomy had conflicting results and varying in doses. The objective is to compare perioperative bleeding in major laminectomy between patients receive doubles doses of tranexamic acids (15 mg/kg and 15 mg/kg) with who receive pacebo (0.9% NaCl).

Conditions

Interventions

DRUG

tranexamic acid

Transamine acts as antifibrinolysis which looks alike 0.9% NaCl (placebo)

DRUG

0.9% NaCl

0.9% NaCL (NSS) is clear fluid which looks alike tranexamic acid

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Manee Raksakietisak, MD · Mahidol University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-06-30
Primary Completion
2013-12-31
Completion
2013-12-31

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01643135 on ClinicalTrials.gov