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Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid Illnesses

NCT05419830 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-12-17

Study results available
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Summary

In this study the investigators target three common and comorbid illnesses among older adults namely nocturia or waking at night to void, poor sleep and hypertension. The aim of this proposal is to test behavioral sleep intervention to improve sleep and nocturia vs switching the time of antihypertensive administration to improve nighttime and in turn daytime blood pressure control.

Conditions

Interventions

BEHAVIORAL

BBTI

Participants randomized to BBTI will receive 45- to 60-minute individual intervention session followed by a 30-minute follow-up session 2 weeks later, and 20-minute telephone calls after 1 and 3 weeks. BBTI will focus on four behaviors that promote sleep and discussion of homeostatic and circadian mechanisms of human sleep regulation. These four interventions are simple to conceptualize and implement, and constitute the core of efficacious multi-modal behavioral treatments for insomnia.

OTHER

PM antihypertensive dosing or Chronotherapy

participants will be asked to switch their conventional once daily non-diuretic antihypertensive to bedtime

OTHER

AM antihypertensive dosing

participants will be asked to continue taking their antihypertensive medication within an hour of awakening

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • University of Pittsburgh

    lead OTHER

Principal Investigators

  • Shachi Tyagi · University of Pittsburgh

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-01
Primary Completion
2023-11-30
Completion
2024-01-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05419830 on ClinicalTrials.gov