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Effect of Total Sleep Deprivation on Vascular Function

NCT04535219 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2023-08-29

No results posted yet for this study

Summary

Insufficient sleep is associated with an increased risk for cardiovascular disease. The causal mechanisms are currently unknown, but may include endothelial dysfunction. The purpose of this study is to examine the influence of sex and aging on the effects of total sleep deprivation on vascular function and whether exercise training attenuates these effects.

Conditions

  • Sleep Deprivation

Interventions

OTHER

Exercise

60 minutes of moderate-intensity treadmill exercise (70% of maximal heart rate determined from the maximal graded exercise test)

OTHER

Supervised Total Sleep Deprivation

Laboratory-monitored total sleep deprivation

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Demetra Christou, PhD · University of Florida

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-07-11
Primary Completion
2022-08-02
Completion
2022-08-02

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04535219 on ClinicalTrials.gov