Neurophysiological Correlates of Cognitive Tasks in Healthy Volunteers -WP3 P003
NCT02899403 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2026-05-22
Summary
In the perspective to better evaluate the efficacy of new treatment strategies for Alzheimer disease (AD), it appears important to develop experimental paradigms to precisely measure cognitive endpoints/biomarkers that may be used in healthy volunteers as tools to validate drug efficacy profile.
The use of Electroencephalography (EEG) may be, therefore, a good candidate. The purpose of the present study is to use EEG to more precisely explore cognitive processes in healthy subjects, with a particular interest in episodic and working memory functions that are usually altered in both AD and Mild Cognitive Impairment (MCI) as well as to better understand underlying neural mechanisms involved in these processes.
Conditions
- Alzheimer Disease
- ELECTROENCEPHALOGRAPHIC VARIANT PATTERN 1 (Disorder)
Interventions
- OTHER
-
Rapid Visual Information Processing (RVIP) test
Rapid Visual Information Processing is a measure of sustained attention.
Sponsors & Collaborators
-
University Hospital, Lille
lead OTHER
Principal Investigators
-
Dominique Deplanque, MD, PhD · University Hospital, Lille
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-05-19
- Primary Completion
- 2020-12-31
- Completion
- 2020-12-31
Countries
- France
Study Locations
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