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Optical Coherence Tomography in Cerebral Amyloidosis

NCT03472482 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 85

Last updated 2018-03-21

No results posted yet for this study

Summary

In this observational study, the investigators aim to evaluate whether changes in the retinal and choroidal circulation, as assessed by Optical Coherence Tomography (OCT) and the quantification of retinal amyloid deposits using auto-fluorescence and hyperspectral retinal imaging, are correlated with the degree and subtype of dementia and with the presence or absence of a positive amyloid scan.

For this purpose, patients with established Alzheimer's Disease (AD) and Lewy Body Dementia (LBD), as well as amyloid positive and amyloid negative Mild Cognitive Impairment (MCI) and aged matched cognitively intact patients will be included in this cross-sectional study.

Conditions

Interventions

DIAGNOSTIC_TEST

non-invasive retinal imaging

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Principal Investigators

  • Evelien Vandewalle, MD PhD · UZ Leuven/KU Leuven

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-25
Primary Completion
2018-12-31
Completion
2019-12-31

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03472482 on ClinicalTrials.gov