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OCT Angiography in Arteritic and Non Arteritic Anterior Ischemic Neuropathy

NCT03642899 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 17

Last updated 2019-07-10

No results posted yet for this study

Summary

Anterior ischaemic optic neuropathy results from infarction of retrolaminar portion of the optic nerve head, caused by occlusion of the posterior ciliary artery. Non arteritic anterior ischaemic optic neuropathy affects more frequently people between 50 and 70 years of age, with vasculopathic risk factors. Arteritic anterior ischaemic optic neuropathy is caused by the Horton disease, affects an older population and is an ophthalmologic emergency because of the bilateralisation's risk.

The aim of this study is to compare the peripapillar vascular density of anterior ischaemic optic neuropathy eyes (arteritic and non arteritic) with normal eyes after the disappearance of the papillar edema, with oCT-angiography.

The investigators will include patients with anterior ischaemic optic neuropathy and normal patients. For each participant, the investigators will estimate the best visual acuity, intra-ocular pressure, make a fondus, measurement of retinal nervous layer thickness, ganglionar cells layer thickness, and a macular and papillar OCT angiography during a consultation (duration 30 min).

The investigators will be able to know if

* there is a modification of the peripapillary vascularisation subsequent to the occlusion of the posterior ciliary artery
* there is a difference between arteritic and non arteritic anterior ischaemic optic neuropathy,
* there is a repercussion of the neuropathy on the retinal layers,
* there is a difference in peripapillar vascularisation by age.

Conditions

  • Neuropathy, Optic

Sponsors & Collaborators

  • Poitiers University Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-08-29
Primary Completion
2019-06-04
Completion
2019-06-04

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03642899 on ClinicalTrials.gov