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Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers

NCT04794634 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2025-12-08

No results posted yet for this study

Summary

Alzheimer disease is hard, long and expensive to diagnose. In order to help the clinician, a new biomarker in Alzheimer disease seems to be very useful. The retina, as a window of the brain, could offer a new way to diagnose this common disease. Indeed, a retinal atrophy could especially appear in Alzheimer disease. Besides, many aspects about retinal alteration, visual function and their link with the disease deserve to be more explored. So as to fill these gaps, a new study about retinal specificity in Alzheimer disease appears to be relevant.

Conditions

  • Optical Coherence Tomography
  • Optical Coherence Tomography Angiography
  • Retinal Thickening
  • Alzheimer Disease
  • Lewy Body Disease
  • Retina
  • Cortical Atrophy
  • Retinal Nerve Fibres Layer

Interventions

DIAGNOSTIC_TEST

Optical coherence tomography (OCT)

to make a complete ophthalmological and neurological examination, an OCT to AD and to compare their results with LD and controls subjects

DIAGNOSTIC_TEST

Optical coherence tomograpohy angiography (OCTA)

to make a complete ophthalmological and neurological examination, an OCT and OCTA, to AD and to compare their results with LD and controls subjects

Sponsors & Collaborators

  • Centre Hospitalier Universitaire, Amiens

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-13
Primary Completion
2023-06-23
Completion
2025-12-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04794634 on ClinicalTrials.gov