Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease
NCT03455686 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2024-05-21
Summary
This is a single centre exploratory study that aims to apply hyperpolarized xenon-129 (129Xe) magnetic resonance imaging (MRI) methods and measurements in individual patients with and without lung disease to better understand lung structure and function and evaluate response to therapy delivered as a part of clinical care.
Conditions
- Asthma
- Chronic Obstructive Pulmonary Disease
- Bronchiectasis
- Emphysema
- Pulmonary Fibrosis
- Bronchopulmonary Dysplasia
- Alpha 1-Antitrypsin Deficiency
- Sarcoidosis, Pulmonary
Interventions
- OTHER
-
Hyperpolarized 129Xe MRI
Magnetic resonance imaging (MRI) using inhaled hyperpolarized 129Xe gas is a research approach for the non-invasive visualization and measurement of lung structure and function.
Sponsors & Collaborators
-
St. Joseph's Healthcare Hamilton
collaborator OTHER - lead OTHER
Principal Investigators
-
Parameswaran Nair, MD, PhD · McMaster University
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2018-04-19
- Primary Completion
- 2024-10-31
- Completion
- 2024-12-31
Countries
- Canada
Study Locations
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