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Goal of Open Lung Ventilation in Donors

NCT03439995 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 154

Last updated 2021-05-06

No results posted yet for this study

Summary

The primary goal of this study is to assess whether ventilation of deceased organ donors with an open lung protective ventilatory strategy will improve donor lung utilization rates and donor oxygenation compared to a conventional ventilatory strategy.

Conditions

  • Brain Death
  • Organ Donation
  • Organ Transplant Failure or Rejection

Interventions

OTHER

Open lung protective ventilation

Higher PEEP, lower tidal volume mechanical ventilation

OTHER

Conventional ventilation

Lower PEEP, standard tidal volume mechanical ventilation

Sponsors & Collaborators

Principal Investigators

  • Lorraine B Ware, MD · Vanderbilt University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
13 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-07-09
Primary Completion
2020-01-01
Completion
2021-01-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03439995 on ClinicalTrials.gov