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Effort of Breathing Guided Ventilator Protocol

NCT02989246 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2024-10-30

Study results available
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Summary

This pilot study tests the feasibility of using a computerized ventilator management protocol seeking to encourage lung protective ventilation during the acute phase of ventilation, and esophageal manometry based titration of ventilator settings during the weaning phase of ventilation, for children with acute respiratory failure. The investigators hypothesize that such an approach will reduce time on mechanical ventilation, largely by preserving diaphragm muscle function.

Conditions

  • Ventilators, Mechanical
  • Work of Breathing

Interventions

OTHER

Ventilator protocol

Open loop ventilator management by a computer based protocol

DEVICE

Esophageal Catheter

Esophageal manometry measurements of patient effort of breathing will be used to guide the protocol recommendations

Sponsors & Collaborators

Principal Investigators

  • Robinder Khemani, MD · Children's Hospital Los Angeles

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
37 Weeks
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-02-01
Primary Completion
2017-10-18
Completion
2018-12-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02989246 on ClinicalTrials.gov