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The Effects of Types of Fruits and Vegetables on Vascular Function

NCT03410342 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2022-03-22

No results posted yet for this study

Summary

The CIRCUS study is a randomised controlled, cross-over trial to evaluate the effects of increased intakes of citrus fruits and cruciferous vegetables on vascular function in 36 untreated, prehypertensive participants.

Conditions

  • Blood Pressure
  • Vascular Stiffness
  • Cardiovascular Risk Factor

Interventions

OTHER

LFV

1 apple/banana/small bunch of grapes per day plus 1 portion of carrot/pepper/tomato per day

OTHER

HFV

4 portions of fruits (apples, bananas, grapes, pears) plus 4 portions of vegetables (carrots, cucumber, sweet peppers, tomatoes), of commonly consumed types per day excluding citrus fruits, cruciferous and allium vegetables.

OTHER

CC

4 portions of citrus fruits (clementines, grapefruits, lemons, oranges) plus 4 portions of cruciferous vegetables (broccoli, brussels sprouts, cauliflower, kale, savoy cabbage) per day.

Sponsors & Collaborators

Principal Investigators

  • Linda Oude Griep, PhD · MRC Epidemiology Unit, University of Cambridge

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-09-04
Primary Completion
2021-06-21
Completion
2021-06-21

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03410342 on ClinicalTrials.gov