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Combined Intracerebral and Jugular Bulb Microdialysis

NCT03314779 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2019-02-28

No results posted yet for this study

Summary

The first aim of this study is to investigate the frequency and severity of a specific pathological metabolic pattern, mitochondrial dysfunction, of the brain in comatose patients under neurocritical care. This pattern is recognized as a complication after compromised blood flow to the brain and may be amenable to treatment. The other main aim of this study is to correlate patterns of metabolites between brain and jugular venous blood. It is probable but not proven that jugular venous microdialysis can mirror the global metabolic state of the brain.

Conditions

  • Subarachnoid Hemorrhage
  • Hypoxia Ischemia, Cerebral
  • TBI
  • Meningitis

Sponsors & Collaborators

  • Region of Southern Denmark

    collaborator OTHER

  • Odense University Hospital

    lead OTHER

Principal Investigators

  • Frantz Rom Poulsen, MD, PhD · Consultant, Professor, Research leader

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-08-28
Primary Completion
2018-07-01
Completion
2018-07-01

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03314779 on ClinicalTrials.gov