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Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis Values

NCT01028339 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2012-08-08

No results posted yet for this study

Summary

The purpose of this study is to determine whether hypertonic saline is as much effective as mannitol to treat intracranial hypertension after traumatic brain injury and has at least the same effects on PtiO2 and cerebral metabolism studied through microdialysis.

Conditions

Interventions

DRUG

Hypertonic saline

2 mL/kg of 7.5% hypertonic saline associated to hydroxyethyl starch

DRUG

Mannitol

Mannitol

Sponsors & Collaborators

  • Direction Centrale du Service de Santé des Armées

    lead OTHER

Principal Investigators

  • Henry BORET, MD · Direction Centrale du Service de Santé des Armées

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-07-31
Primary Completion
2012-06-30
Completion
2012-12-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01028339 on ClinicalTrials.gov