Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia
NCT00332267 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2008-09-04
Summary
The objective of the present protocol is to study whether a low level of oxygen in the blood will affect the immune response to as well as cerebral blood flow and metabolism during an infection and, conversely, whether the acute systemic and cerebral physiologic response to hypoxia is modified by an ongoing inflammatory response.
Conditions
- Hypoxia
- Endotoxemia
- Healthy
Interventions
- PROCEDURE
-
Endotoxin infusion, Normobaric hypoxia
Sponsors & Collaborators
-
The Ministry of Science, Technology and Innovation, Denmark
collaborator OTHER_GOV -
H:S, Denmark
collaborator UNKNOWN -
The Danish National Research Foundation, Denmark
collaborator UNKNOWN -
Rigshospitalet, Denmark
lead OTHER
Principal Investigators
-
Sarah Taudorf, MD · Rigshospitalet, Denmark
-
Kirsten Moller, MD, PhD · Rigshospitalet, Denmark
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2006-05-31
- Primary Completion
- 2006-07-31
- Completion
- 2006-07-31
Countries
- Denmark
Study Locations
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