Cerebral Blood Flow and Metabolism During Hypoxia and Endotoxemia

NCT00332267 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2008-09-04

No results posted yet for this study

Summary

The objective of the present protocol is to study whether a low level of oxygen in the blood will affect the immune response to as well as cerebral blood flow and metabolism during an infection and, conversely, whether the acute systemic and cerebral physiologic response to hypoxia is modified by an ongoing inflammatory response.

Conditions

Interventions

PROCEDURE

Endotoxin infusion, Normobaric hypoxia

Sponsors & Collaborators

  • The Ministry of Science, Technology and Innovation, Denmark

    collaborator OTHER_GOV
  • H:S, Denmark

    collaborator UNKNOWN
  • The Danish National Research Foundation, Denmark

    collaborator UNKNOWN
  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Sarah Taudorf, MD · Rigshospitalet, Denmark

  • Kirsten Moller, MD, PhD · Rigshospitalet, Denmark

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-05-31
Primary Completion
2006-07-31
Completion
2006-07-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00332267 on ClinicalTrials.gov