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The Effect of Menstrual Cycle On IL-6, TNF-α And Periodontal Status

NCT03281109 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2018-02-06

No results posted yet for this study

Summary

Aim: Women's menstrual cycle is controlled by the secretion of sex hormones. Sex steroid hormones are thought to be affect to periodontal tissues, wound healing, periodontal disease progression and bone turn over. The aim the study is to evaluate clinical periodontal parameters and interleukin- 6 (IL-6) and tumor necrosis factor alpha (TNF-α) levels in gingival crevicular fluid (GCF) in menstrual cycle.

Material and methods: Twenty-five patients were included in this study clinical periodontal parameters and levels of IL-6 and TNF α in gingival crevicular fluid were evaluated at three periods of menstrual cycle (menstruation day (MD)-ovulation day(OD)-premenstruation day (PmD)). Levels of IL-6 and TNF α in gingival crevicular fluid were determined by ELISA.

Conditions

  • Menstrual Cycle-Associated Gingivitis

Interventions

DIAGNOSTIC_TEST

diagnosis

diagnosis with ELISA

Sponsors & Collaborators

  • Yuzuncu Yıl University

    lead OTHER

Principal Investigators

  • hacer sahin aydinyurt · yuzuncu yil universtiy

Eligibility

Min Age
20 Years
Max Age
29 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-26
Primary Completion
2018-09-30
Completion
2018-09-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03281109 on ClinicalTrials.gov