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Chronic Periodontitis and Polycystic Ovary Syndrome

NCT02954120 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 88

Last updated 2020-01-18

No results posted yet for this study

Summary

Background: The aim of this study was to investigate the levels of malondialdehyde (MDA), total antioxidant status (TAS), 8-hydroxy-2´- deoxyguanosine (8-OHdG) in blood serum and saliva samples in female patients with chronic periodontitis (CP) and to compared healthy individuals.

Materials and Methods: A total of 88 women were into four groups each which were consisted of twenty-two subjects. Groups were designed as periodontally and systemically healthy women (PCOS-CP-); periodontally healthy women with polycystic ovary syndrome (PCOS) (PCOS+CP-), systemically healthy women with CP (PCOS-,CP+) and women with PCOS and CP (PCOS+CP+). Serum and salivary samples were obtained, clinical periodontal parameters were recorded. MDA, TAS, 8-OHdG levels were measured as biochemically.

Conditions

  • Polycystic Ovary Syndrome
  • Chronic Periodontitis

Interventions

OTHER

no intervention provided

Sponsors & Collaborators

  • Bezmialem Vakif University

    lead OTHER

Principal Investigators

  • Nesrin Saruhan, PhD · Eskisehir Osmangazi Üniversitesi

  • Cenk Fatih Çanakcı, Prof · Ataturk University

  • Saime Ozbek Sebin, Dr · Ataturk University

  • Humeyra Canakcı, Dr · Buhara Hastanesi

  • Metin İngeç, Prof · Ataturk University

  • Ufuk Sezer, Phd · Özel Klinik

  • Ebru Saglam, PhD · Saglik Bilimleri Universitesi

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-05-31
Primary Completion
2015-05-31
Completion
2015-09-30

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02954120 on ClinicalTrials.gov