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Prevalence of Trephined Syndrome After Decompressive Craniectomy

NCT03186157 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2020-11-18

No results posted yet for this study

Summary

Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy. The symptomatology is varied but includes headache, aggravation of a hemisyndrome or cognitive disorders, often has an orthostatic component and improves or disappears with cranioplasty. The incidence of Trephined Syndrome has been reported between 7% and 26%. However, it might be underestimated if the course of cognitive functions before and after cranioplasty were insufficiently documented.

Conditions

  • Trephined Syndrome
  • Sinking Skin Flap Syndrome
  • Traumatic Brain Injury
  • Stroke
  • Post Operative Hemorrhage
  • Post-Op Complication
  • Post-Op Infection

Interventions

PROCEDURE

Decompressive craniectomy

Decompressive craniectomy is a surgical procedure used to treat patients with acute intractable intracranial hypertension. It includes removing a large portion of lateral skull wall in order to alleviate the effects of increased intracranial pressure and allow the brain to expand.

PROCEDURE

Cranioplasty

Cranioplasty is a routine neurosurgical procedure to repair the continuity of the bone tissue of the skull with autologous bone or synthetic bone flap from heterologous material.

Sponsors & Collaborators

  • University Hospital, Geneva

    lead OTHER

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-16
Primary Completion
2017-03-31
Completion
2017-03-31

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03186157 on ClinicalTrials.gov