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Iron Absorption From Iron-enriched Aspergillus Oryzae

NCT03156712 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 17

Last updated 2017-05-18

No results posted yet for this study

Summary

Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress. The objective of this study was to determine how quickly iron enters into blood stream from the iron-enriched Asperigillus oryzae (AspironTM, ASP) in contrast to ferrous sulfate. Seventeen healthy, female subjects (18-35 y) were randomized, double blind, cross-over experimental design with three treatments: 10 mg iron as FeSO4 and ASP as well as 20 mg iron as ASP.

Conditions

  • Iron-deficiency
  • Absorption; Iron
  • Anemia, Iron Deficiency
  • Bioavailability
  • Serum Iron

Interventions

DIETARY_SUPPLEMENT

Ferrous sulfate

The intervention is the ASP, a natural form of iron supplement and compared to a widely used dietary iron supplement ferrous sulfate in terms of serum iron response over a 4h period.

Sponsors & Collaborators

  • Iowa State University

    lead OTHER

Principal Investigators

  • Manju B Reddy, Ph.D. · Iowa State University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-05-29
Primary Completion
2013-11-20
Completion
2014-02-13

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03156712 on ClinicalTrials.gov