A Trial on the GI of Spaghetti Versus Rice as Mixed Meals

Summary

Pasta and rice are two of the most commonly consumed grains worldwide, where the former has a low GI (e.g. spaghetti) and the latter, usually (as it depends on the type) has a higher GI (e.g. white rice). The most typical ways in which pasta and rice are consumed are with the addition of oil or tomato sauce, and are recommended to be consumed in this way in the Mediterranean diet. The Mediterranean diet has been demonstrated to reduce the risk of cardiovascular disease, improve glycemic control and is encouraged in many clinical guidelines globally for both cardiovascular risk reduction. Some studies have explored the differences in glycemic response of different carbohydrate foods consumed with the addition of fat demonstrating that the glycemic response is indeed reduced.However, the GI may remain of importance even when other means to reduce glycemic response are introduced.

The investigators therefore designed a randomized controlled crossover study to explore whether the addition of fat in the form of commonly consumed sauces which are recommended as part of a Mediterranean diet, affects the difference in glycemic response between a commonly consumed low GI and a higher GI carbohydrate food.

Conditions

• Dietary Modification

Interventions

OTHER

Glucose #1

50g available carbohydrate

OTHER

Glucose #2

50g available carbohydrate

OTHER

Glucose #3

50g available carbohydrate

OTHER

Spaghetti

50g available carbohydrate

OTHER

Rice

50g available carbohydrate

OTHER

Spaghetti + Tomato Sauce

50g available carbohydrate

OTHER

Rice + Tomato Sauce

50g available carbohydrate

OTHER

Spaghetti + Pesto

50g available carbohydrate

OTHER

Rice + Pesto

50g available carbohydrate

Sponsors & Collaborators

• University of Parma

  lead OTHER

Principal Investigators

• Francesca Scazzina, PhD · Department of Food and Drug, University of Parma

• Furio Brighenti, PhD · Department of Food and Drug, University of Parma

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2017-04-27

Primary Completion

2018-03-12

Completion

2018-04-30

Countries

• Italy

Study Locations