A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer
NCT03027284 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2020-05-19
Summary
The main purpose of this study is to evaluate tolerability of merestinib monotherapy or in combination with other anti-cancer agents in Japanese participants with advanced and/or metastatic cancer.
Conditions
- Advanced Cancer
- Metastatic Cancer
- Biliary Tract Carcinoma
- Cholangiocarcinoma
- Gall Bladder Carcinoma
- Solid Tumor
- Non-Hodgkin's Lymphoma
Interventions
- DRUG
-
Merestinib
Administered orally
- DRUG
-
Administered IV
- DRUG
-
Administered IV
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) · Eli Lilly and Company
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-02-03
- Primary Completion
- 2019-06-20
- Completion
- 2020-03-17
Countries
- Japan
Study Locations
More Related Trials
-
A Study of LY2875358 in Japanese Participants With Advanced Cancer
NCT01602289 ·Status: COMPLETED ·Phase: PHASE1
-
Lapatinib in Combination With Capecitabine in Japanese Patients With Metastatic Breast Cancer
NCT00477464 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY2603618 in Combination With Gemcitabine in Participants With Solid Tumors
NCT01341457 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer
NCT04071262 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3007113 in Participants With Advanced Cancer
NCT01463631 ·Status: COMPLETED ·Phase: PHASE1
-
An Investigational Study of NKTR-214 Combined With Nivolumab in Japanese Participants With Advanced Solid Tumors
NCT03745807 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY2801653 in Advanced Cancer
NCT01285037 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial of LBL-024 Monotherapy or Combination Drug in Patients With Triple Negative Breast Cancer
NCT07281976 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
NCT02057133 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study Of Oral Palbociclib (PD-0332991), A CDK4/6 Inhibitor, As Single Agent In Japanese Patients With Advanced Solid Tumors Or In Combination With Letrozole For The First-Line Treatment Of Postmenopausal Japanese Patients With ER (+) HER2 (-) Advanced Breast Cancer
NCT01684215 ·Status: COMPLETED ·Phase: PHASE2
-
A Safety Study of Lirilumab in Combination With Nivolumab or in Combination With Nivolumab and Ipilimumab in Advanced and/or Metastatic Solid Tumors
NCT03203876 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3023414 in Participants With Advanced Cancer
NCT01655225 ·Status: COMPLETED ·Phase: PHASE1
-
Abemaciclib, Palbociclib or Dalpiciclib Combined with Endocrine Therapy As First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer
NCT06344780 ·Status: ACTIVE_NOT_RECRUITING
-
A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers
NCT02919696 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic HR+/HER2- Breast Cancer Who Have Previously Failed Endocrine Therapy
NCT07071337 ·Status: RECRUITING ·Phase: PHASE3
-
LM-108 in Combination With PD-1 Based Treatment for Patients With Recurrent or Metastatic Triple - Negative Breast Cancer
NCT06387628 ·Status: RECRUITING ·Phase: PHASE2
-
A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer(PANKU-Breast02)
NCT06382142 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases
NCT03500380 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer
NCT06279364 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of AK117/AK112 in Metastatic Triple-Negative Breast Cancer
NCT05227664 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 1b Trial of Lenvatinib Plus Pembrolizumab in Participants With Selected Solid Tumors
NCT03006887 ·Status: COMPLETED ·Phase: PHASE1
-
Lynparza Breast Cancer Clinical Experience Investigation
NCT03590938 ·Status: COMPLETED
-
SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer
NCT05445908 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer
NCT02980341 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of SI-B003 or BL-B01D1+SI-B003 in Patients With Unresectable Locally Advanced or Recurrent Metastatic HER2 Negative Breast Cancer
NCT06042894 ·Status: RECRUITING ·Phase: PHASE2