Abemaciclib, Palbociclib or Dalpiciclib Combined with Endocrine Therapy As First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer
NCT06344780 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-12-20
Summary
A multi-center, real world study to evaluate the clinical outcomes and safety of Abemaciclib, Palbociclib or Dalpiciclib combined with endocrine therapy as first-line treatment in HR Positive, HER2 Negative unresectable or metastatic Breast Cancer.
Conditions
Sponsors & Collaborators
-
Fudan University
lead OTHER
Principal Investigators
-
Biyun Wang, Professor · Fudan University
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-20
- Primary Completion
- 2024-10-01
- Completion
- 2025-02-01
Countries
- China
Study Locations
More Related Trials
-
Treatment After Palbociclib-containing Regimens
NCT04517318 ·Status: COMPLETED
-
Palbociclib Combine With Anti-HER2 Therapy in Triple Positive ABC
NCT05969184 ·Status: UNKNOWN ·Phase: PHASE2
-
A Real-world Efficacy and Safety Study of Amlotinib for HER2-negative Advanced Breast Cancer
NCT06340165 ·Status: RECRUITING
-
Neoadjuvant Dose-dense EC Followed by ABX With PD-1 for Triple Negative Breast Cancer Patients
NCT04418154 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Negative Breast Cancer and Other Solid Tumors
NCT06503783 ·Status: RECRUITING ·Phase: PHASE1
-
Adebrelimab Combined With Dalpiciclib and Standard Endocrine Therapy for HR+/HER2 - Advanced Breast Cancer
NCT06149130 ·Status: RECRUITING ·Phase: PHASE2
-
Chidamide in Combination With Abemaciclib and Endocrinotherapy(Doctor's Choice) in Breast Cancer Patients Previously Treated With Palbociclib
NCT05464173 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Retrospective Real-world Study of Abemaciclib in HR+ Breast Cancer
NCT06341283 ·Status: NOT_YET_RECRUITING
-
Dalpiciclib in HR+/HER2- ABC
NCT06301438 ·Status: RECRUITING
-
A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC
NCT07002177 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic HR+/HER2- Breast Cancer Who Have Previously Failed Endocrine Therapy
NCT07071337 ·Status: RECRUITING ·Phase: PHASE3
-
Chemotherapy Omission in ER+/HER2- Breast Cancer With 1-3 Positive Lymph Nodes Receiving Extended Adjuvant Abemaciclib
NCT06341621 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer
NCT02763566 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Dual Anti-HER2 Therapy (Lapatinib and Trastuzumab) Plus Chemotherapy in HER2-positive MBC
NCT04001634 ·Status: COMPLETED
-
Tumor Response Time of Palbociclib in Combination With AI in Real-world Chinese Patients
NCT04858997 ·Status: UNKNOWN ·Phase: PHASE2
-
Albumin-bound Paclitaxel、Dalpiciclib and AI in ER-Low (1%-10%) HER2-ABC
NCT06711094 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer(PANKU-Breast02)
NCT06382142 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Comparative Effectiveness of Palbociclib Plus AI Versus Fulvestrant for HR+/HER2- ABC
NCT05000736 ·Status: UNKNOWN
-
Apatinib Combined With Paclitaxel and Carbopatin Intensive Regimen in Neoadjuvant Therapy for Locally Advanced Triple-negative Breast Cancer
NCT03735082 ·Status: UNKNOWN ·Phase: PHASE2
-
Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer
NCT06447623 ·Status: RECRUITING ·Phase: PHASE3
-
RWS of Paclitaxel Liposome Combined With Anti-HER-2 Monoclonal Antibody
NCT06481553 ·Status: ACTIVE_NOT_RECRUITING
-
Palbociclib, Trastuzumab,Pyrotinib and Fulvestrant Treatment in Patients With Brain Metastasis From ER/PR Positive, HER-2 Positive Breast Cancer: A Multi-center, Prospective Study in China
NCT04334330 ·Status: UNKNOWN ·Phase: PHASE2
-
Exploratory Study of Advanced Breast Cancer in HER2 Positive Patients With Failure of Multi-line Therapy Treated by Combination of Inetetamab (Cipterbin) + PD-1 Inhibitor Combined With Utidelone.
NCT04681287 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of SHR-A2102 Combined Other Antitumor Drugs in Advanced Breast Cancer
NCT07041437 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
A Study of Abemaciclib in Indian Women With Advanced Breast Cancer
NCT04707196 ·Status: COMPLETED ·Phase: PHASE4