A clinical trial showed that digital symptom check-ins improved quality of life for advanced cancer patients, especially underserved groups. Researchers are also advancing survivorship care and investigating ageing biology to improve recovery in older patients.
Most advanced cancer patients misunderstand whether their treatment is curative. Honest prognosis discussions improve outcomes without worsening distress, while diagnostic delays persist; pathologist involvement can speed treatment.
Replimune said the FDA issued a complete response letter for its RP1 plus nivolumab application in advanced melanoma. The company disputed the agency’s assessment and said it will cut jobs and scale back U.S. manufacturing.
The FDA has granted Fast Track designation to Pasithea Therapeutics' PAS-004 for treating NF1-associated plexiform neurofibromas. The designation facilitates expedited development and review for serious conditions with unmet medical needs. Pasithea is currently conducting Phase 1/1b trials of the next-generation MEK inhibitor in patients with these tumors.
Immunotherapy is increasingly used in earlier cancer stages before or after surgery across seven tumor areas. Research shows neoadjuvant and adjuvant immunotherapy can reduce recurrence risk and improve immune recognition of tumor cells. However, challenges remain including side effects, costs, and determining which patients benefit most from earlier treatment.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07761988 |
The FamilyStrong Pilot Randomized Trial |
NOT_YET_RECRUITING | NA |
| NCT07737899 |
Primary Palliative Care - a Feasibility Cluster Trial |
NOT_YET_RECRUITING | NA |
| NCT07712237 |
Web-Based Advance Care Planning for Patients With Advanced Cancer |
COMPLETED | NA |
| NCT07659158 |
Virtual Group Resilient Living Program For Patients Living With Advanced Cancer |
RECRUITING | NA |
| NCT07654933 |
Physiotherapy Effects on Function, Ambulation, and Independence in Palliative Cancer Care |
COMPLETED | NA |
| NCT07648160 |
Contrast-enhanced CBCT With C-arm HyperSight Technology |
RECRUITING | NA |
| NCT07644533 |
Electroacupuncture for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Advanced Cancer |
NOT_YET_RECRUITING | NA |
| NCT07636382 |
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain |
RECRUITING | NA |
| NCT07605962 |
Phase 1/2 Study of UI-102 in Selected Advanced Cancers |
RECRUITING | PHASE1/PHASE2 |
| NCT07540468 |
Safety Evaluation of Bioactive Glass Based Bone Cement Combined With Ultrasound in Implantation for Metastatic Bone Tumors |
NOT_YET_RECRUITING | NA |
