Pasta and Other Durum Wheat-based Products: Effects on Post-prandial Glucose Metabolism

Summary

Carbohydrate-based products can influence the post-prandial glycemic response differently based on their ability to be digested, absorbed and to affect rises in plasma glucose. Pasta is one of the major carbohydrate-rich foods consumed in Italy. Studies from the literature describe a lower glycemic response after the consumption of pasta compared with other wheat-based products, such as bread. Among the factors affecting post-prandial glycemia after consumption of carbohydrate-based products, the technological process represents a central one.In fact, the different technological processes alter the food matrix which can affect the post-prandial metabolism of glucose differently. Thus, the present study aims at investigating the effect induced by the principal steps of the process of pasta production on the reduction of post-prandial glycemic response (post-prandial glucose, insulin, GLP-1, GIP plasma concentrations).

Conditions

• Dietary Modification

Interventions

OTHER

Glucose

Glucose monohydrate (55 g) dissolved with 500 mL of water

OTHER

Semolina soup

Semolina soup (322 g) eaten with 500 mL of water

OTHER

Bread

Bread (122 g) eaten with 500 mL of water

OTHER

Penne (fresh)

Cooked penne (132 g) eaten with 500 mL of water

OTHER

Penne (dry)

Cooked penne (142 g) eaten with 500 mL of water

OTHER

Spaghetti (dry)

Cooked spaghetti (142 g) eaten with 500 mL of water

Sponsors & Collaborators

• University of Parma

  lead OTHER

Principal Investigators

• Francesca Scazzina, Professor · Department of Food Science, University of Parma

• Furio Brighenti, Professor · Department of Food Science, University of Parma

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2015-09-30

Primary Completion

2016-06-30

Completion

2016-07-31

Countries

• Italy

Study Locations